Explore 3D chemical space through LCC’s virtual libraries, which have been enumerated based on our novel collection of sp3-rich synthons
1.4Bn ULVL, Focused Libraries, Covalent VL
3D-rich, stereodefined, diverse, novel, and synthetically tractable. The library has been designed by reaction-based enumeration of LCC’s proprietary (chiral) scaffolds, co-located with our parallel synthesis laboratory for rapid synthesis of hits.
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Find out more about LCC’s ULVL
LCC is excited to announce our new Kinase-Focused VL featuring pre-defined near-neighbour analogues:
Building on the foundations of our enantiopair fragment sets, we have continued our investment in the field to provide high-quality covalent compounds for drug discovery and chemical biology groups.
Our covalent VL includes >800k compounds functionalised with the same warhead and it has been enumerated based on the following scheme:
The workflow used for the enumeration is flexible and can be adapted to any commercial/bespoke warhead that can be installed on the reactive nitrogen.
All chemical transformations have been validated in our parallel synthesis lab as well as the incorporation of several common warheads.
LCC’s combination of novel synthons, computational expertise, and a parallel synthesis laboratory mean we can support your library needs. To read more about the value of partnering with us for virtual screening projects, please visit our parallel synthesis webpage. To discuss further, please get in touch.
