Explore new chemical space with access to 3D-rich, covalent, and enantiopair fragments
LCC’s Parallel Synthesis Laboratory is co-located with our in-stock synthons, meaning we can efficiently synthesise sets of covalent fragments. With a focus on chirally-pure material, we specialise in providing sets of enantiomers with absolute stereochemistry determined. Racemic and achiral material is also available.
Parameter | Count |
---|---|
MW | ≤300 |
Rotatable Bonds | ≤3 |
H-donors | 3 |
AlogP | ≤3 |
Chiral Centres | 0 - 3 |
Synthetic Handle Count | 0 - 3 |
% homochiral | 42% |
Fsp3 | ≥0.7 (20%) ≥0.5 - <0.7 (30%) ≥0.3 - <0.5 (30%) ≥0 - <0.3 (20%) |
Move from Ro3 (fragment-like) to Ro4 (lead-like) space using LCC's platform, which has been designed through combining our 3D-rich fragment library with computational expertise and parallel synthesis capabilities.