Fragment Libraries

3D-rich Fragment Libraries

Library Design

LCC have designed a 3D-rich fragment library based on sp3-rich heterocyclic cores:

Fragments - Key Criteria

  • Ro3 compliant
  • Not regularly more than 1 chiral centre
  • Fraction sp3 generally between 0.3-0.7
  • Cyclic-based structures >> Low number of rotatable bonds
  • Good predicted aqueous solubility
Liverpool ChirChem 3D Rich Fragments

For more information or to enquire about the availability of our fragment libraries please contact

samuel.kirkwood@liverpoolchirochem.com