(including scaffolds for DEL synthesis)
(3D vector exploration)
(nearest neighbours for rapid SAR analysis)
(FFS or FTE)
(e.g. Asymmetric Hydrogenation and Pd-coupling)
(for APIs or key intermediates)
Liverpool ChiroChem (LCC) is a chemical technology innovator that produces chiral small molecules for biotech/pharmaceutical R&D. Our specialist products can be used as building blocks, fragments and screening compounds to enable small molecule drug discovery. Our chemical technologies provide efficient access to novel chiral building blocks to allow facile access to new chemical space for hit identification and desirable pharmacokinetic properties for effective lead optimisation. Our proprietary products are ideally suited for DNA-encoded library synthesis and Fragment Based Lead Discovery, which many medicinal chemists consider to be the two leading areas of modern-day drug discovery.
Headquarters and R&D Centre
North West England
Analytical Centre & Scale-up Laboratory
LCC’s core technology:
LCC’s catalytic methods give access to a wide range of chiral amines in excellent enantiomeric purity. Our initial focus is on the production and supply of chiral piperidines and other sp3-rich nitrogen heterocycles , which are of great importance to drug discovery and development due to their excellent pharmacokinetic properties e.g. improved solubility and bioavailability.
LCC's technologies were developed through years of research in the areas of asymmetric hydrogenation and Pd-coupling. LCC now provide collaborate services with our customers to optimise key steps in synthetic routes.
LCC’s core strengths:
- Production of privileged heterocyclic building blocks using expert synthetic technologies, thus making them readily accessible, chirally pure and available on scale
- ee data provided for every chiral product
- Excellent chemical and enantiomeric purity
- In-depth knowledge of asymmetric hydrogenation and Pd-coupling