Reach new opportunities in your PROTACs programme(s)
by accessing novel type of linkers.
USE LCC’S SEMI-FLEXIBLE LINKERS TO CONTROL THE STRUCTURAL ORIENTATION OF YOUR PROTACS.
While efforts are focusing on the protein of interest ligand, and the E3 ubiquitin ligase recruiting ligand, LCC’s compounds present an original alternative to classical linkers and novel options in terms of overall structure/activity of the PROTACs.
We provide semi-flexible linkers that won’t participate into the binding (no supplementary HBD). With a better control of the structural arrangement, new opportunities arise.
To discuss further opportunities for your PROTACs programe(s) and/or access customised sd-file, please contact our BD Manager, Dr. Marie Hoffmann at marie.hoffmann@liverpoolchirochem.com.
ACCESS 3D-SHAPED SEMI-FLEXIBLE LINKERS
Systematic changes in conformation via exit vectors distribution.
Selected exit vectors for ligand coupling.
Good variety of chain lengths.
No additional HBD ’s.
Reduce number of rotatable bonds.
Racemic and chirally-pure material available.
Interested in novel LINKERS?
If the compounds you are looking for are not yet in our pipeline, but align with our expertise, our R&D Team is ready to tackle whatever comes next. Let’s PROTACs together.
PROTACS CHEMISTRY PORTAL
To assist you in your research effort and tackle a more collaborative and intense approach, we have developed a full-service called the Chemistry Portal.
The portal will help you increase speed, gain time, streamline chemistry processes and reduce costs.
August 2020 – Job Opportunity
TECHNICAL SUPPORT SPECIALIST
Join an innovative CRO, and an international team with various backgrounds in a culturally diverse environment. All employees have a voice and opportunities to develop their careers.
MOtM - July 2020
Enantioenriched 2-Piperidines
By focussing on the development of molecular metal catalysts, his goal is to contribute to greener and more economic organic synthesis. Prof. Xiao rapidly found...
June 2020 - Award
PROFESSOR XIAO WINS 2020 TILDEN PRIZE
Congratulations to Professor Jianliang Xiao, recipient of the prestigious 2020 Tilden Prize from the Royal Society of Chemistry. Having him as a distinguished member of our Scientific Advisory Board is a blessing. Thank you Professor!
News - April 2020 - Funding
NEW £2.25m FUNDING AGREEMENT
Liverpool-headquartered chemical technology business receives £2.25m funding to accelerate its mission
Liverpool ChiroChem, an international chemical technology business whose products form the building blocks to the research and development of new......
News - November 2019 - New Partnership
CRESSET AND LIVERPOOL CHIROCHEM ANNOUNCE COLLABORATION
Cresset, provider of software and contract research services for small molecule drug discovery, and LCC a chemical technology innovator that produces chiral...
